From neuron classification to spiking neural network simulations: a neuroinformatics approach to data-driven computational models

Neuroscience textbooks describe the brain as a massive network of spiking neurons with complex dynamics. Neural circuits, the story goes, are largely defined by the connectivity between axons, reliably propagating all-or-none action potentials to distant targets, and local dendrites integrating synaptic inputs. In this model, activity-dependent plasticity continuously alters synaptic strength, while neurotransmitters determine excitation v. inhibition. Are these ingredients sufficient to explain cognition? If not, what is missing? Tackling these questions for the hippocampal formation, I will show how neuronal diversity is the key to explore the relationship between synapses and behavior.

https://psu.zoom.us/j/94639233394

 

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Event Contact: Rebecca Benson

 
 

About

The Penn State Center for Neural Engineering is a large, interdisciplinary research group that brings together neural engineering-focused researchers from the Penn State College of Engineering, the College of Medicine, the Materials Research Institute, and the Eberly College of Science. Chartered in June 2007, the center occupies 22,000 square feet of space in the Millennium Science Complex.

Center for Neural Engineering

Millennium Science Complex

The Pennsylvania State University

University Park, PA 16802